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Year : 2023  |  Volume : 8  |  Issue : 2  |  Page : 113-123

Pharmacological activity of Ayurveda herbal medicines in anxiety and depression: A review

Department of Shalya Tantra, Institute of Teaching and Research in Ayurveda, Jamnagar, Gujarat 361008, India

Correspondence Address:
Dr. Snehal Sonani
Department of Shalya Tantra, Institute of Teaching and Research in Ayurveda, Jamnagar, Gujarat 361008
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jdras.jdras_74_21

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Research area of herbal psychopharmacology has been increased in this era. It is demand of the era to have comprehensive review of preclinical studies of Ayurveda herbal drugs as antidepressant, anxiolytic, and hypnotic psychopharmacology. On the basis of these findings, further clinical uses as well as better understanding of its mode of action and dosage form can be planned. In this review, search engines such as Ayush Portal, PubMed, DHARA, Research Gate, Scopus, AYU, Google Scholar, Academia, and Google were used to find out widely used psychotropic herbal medicines (last 20 years). A review was conducted to determine mechanisms of action of those drugs, in addition to a scientific review of preclinical trials for the treatment of most common psychiatric clinical conditions, i.e., anxiety and depression. Specific prominence was given to most apparent herbal medicines. Neurochemical as well as epigenetic activities were evident by results of individual herbal medicines in this review. Some drugs were found to be more effective in psychotropic activity, i.e., Kava (Piper methysticum G. Forst.) and Klamath Weed (Hypericum perforatum L.) for anxiety and depression disorders, respectively. However, because many researches have not been produced, caution should be exercised when interpreting the findings.

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